Vertex Pharmaceuticals

Current directors and officers who also hold a role at another S&P 500 company.

• Michel LagardeTMO · OfficerWST · CEO
• Suketu UpadhyayINCY · CFOZBH · CFO
• Charles F. Wagner, Jr.TJX · Director
• Diana McKenzieMET · Director
• Lloyd CarneyV · Director

Latest Schedule 13D/13G filing per holder. Holders that reported falling below 5% are not shown. Index funds usually report once a year.

No 5% holder filings parsed yet for this company.

Open-market purchases and sales reported on Form 4. Grants, option exercises and tax withholding are excluded.

Every 8-K with Item 5.02 (departure, election or appointment of directors and officers). The text is the first paragraph of the item.

1. Oct 20, 2026

   (d) On October 20, 2026, Daniel Brennan was appointed as a new member of the board of directors (the “Board”) of Vertex Pharmaceuticals Incorporated (the “Company”). In connection with the appointment of Mr. Brennan, the size of the Board was increased from ten to eleven members. Mr. Brennan also has joined our Audit and Finance Committee. Mr. Brennan served as the Executive Vice President, Chief Financial Officer of Boston Scientific Corporation, a medical device and healthcare technology company, from January 2014 until his retirement in June 2025. He was the Senior Vice President, Corporate Controller from 2010 through 2013 and, prior to that role, he held various roles of increasing responsibility within the finance function from 1996 through 2009. Mr.

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2. Sep 1, 2026

   On August 27, 2026, Vertex Pharmaceuticals Incorporated (the “Company”) appointed Jonathan Poole as Executive Vice President and Chief Financial Officer of the Company, effective January 1, 2027 (the “Effective Date”). In connection with Mr. Poole’s appointment, Charles F. Wagner, Jr., the Company’s Executive Vice President and Chief Operating & Financial Officer, will cease serving as Chief Financial Officer as of the Effective Date, but will remain Executive Vice President and Chief Operating Officer. Mr. Poole, 51, has been Senior Vice President, Finance at the Company since March 2020. Previously, Mr. Poole served as Chief Financial Officer of Evelo Biosciences, Inc. from March 2018 to March 2020 and as Chief Financial Officer of Genocea Biosciences, Inc. from April 2014 to March 2018. Earlier in his career, Mr.

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3. May 13, 2026

   Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officer On March 27, 2026, the Board of Directors (the "Board") of Vertex Pharmaceuticals Incorporated (the "Company") approved the Vertex Pharmaceuticals Incorporated 2026 Stock and Option Plan (the "2026 Plan"), which replaces the Vertex Pharmaceuticals Incorporated 2013 Stock and Option Plan, subject to shareholder approval. A summary of the principal features of the Plan is set forth under Proposal No. 4 of the Company’s definitive proxy statement filed with the Securities and Exchange Commission on April 2, 2026 (the “Proxy Statement”), which description is incorporated herein by reference. The Plan was approved by the Company's shareholders at the Company's annual meeting of the shareholders held on May 13, 2026 (the "Annual Meeting").

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4. Apr 29, 2026

   On April 28, 2026, Suketu Upadhyay informed the board of directors (the “Board”) of Vertex Pharmaceuticals Incorporated (the “Company”) of his decision not to stand for re-election as a director of the Company at the Company’s 2026 annual meeting of shareholders (the “2026 Annual Meeting”). Mr. Upadhyay has recently been named the forthcoming Chief Financial Officer of Incyte Corporation. Mr. Upadhyay will continue to serve on the Board until the time of the 2026 Annual Meeting. Mr. Upadhyay’s decision to depart from the Board was due to scheduling conflicts associated with his new role at Incyte Corporation and did not involve any disagreement with the Company on any matter relating to its operations, policies or practices. The Board intends to reduce the size of the Board to ten members following the departure of Mr. Upadhyay. Mr.

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5. Aug 4, 2025

   On August 4, 2025, the Company announced the retirement of David Altshuler, Executive Vice President and Chief Scientific Officer, effective August 1, 2026.

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6. Feb 10, 2025

   On February 10, 2025, Vertex Pharmaceuticals Incorporated (the “Company”) announced the retirement of Stuart A. Arbuckle, the Company’s Executive Vice President and Chief Operating Officer, effective on July 1, 2025. The Company also announced the appointment of Charles F. Wagner, Jr. as Chief Operating Officer of the Company and the appointment of Duncan J. McKechnie as Chief Commercial Officer of the Company. Mr. Wagner will remain the Company’s Executive Vice President and Chief Financial Officer following his appointment. The appointment of Messrs. Wagner and McKechnie will be effective on July 1, 2025. Mr. Wagner has held the position of Executive Vice President and Chief Financial Officer since April 2019. For additional biographical information on Mr. Wagner, please see the Company’s Form 10-K filed with the Securities and Exchange Commission on February 15, 2024.

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7. Dec 5, 2023

   (d) On December 5, 2023, Nancy Thornberry was appointed as a new member of the board of directors (the “Board”) of Vertex Pharmaceuticals Incorporated (the “Company”). In connection with the appointment of Ms. Thornberry, the size of the Board was increased from ten to eleven members. Ms. Thornberry served as the Chief Executive Officer of Kallyope, Inc. (“Kallyope”), a private biotechnology company, from 2015 to 2021, and remains on its board of directors and as Chair, R&D . Prior to Kallyope, Ms. Thornberry was self-employed as a consultant to companies in the biotechnology and pharmaceutical industries from 2013 to 2015. Prior to that, she served in roles of increasing responsibility at Merck & Co., Inc., a pharmaceutical company, for more than 30 years, most recently as Senior Vice President and Franchise Head, Diabetes and Endocrinology.

   Read the 8-K filing
8. Oct 5, 2023

   (d) On October 3, 2023, Michel Lagarde was appointed as a new member of the board of directors (the “Board”) of Vertex Pharmaceuticals Incorporated (the “Company”), effective on October 5, 2023. In connection with the appointment of Mr. Lagarde, the size of the Board was increased from nine to ten members. Mr. Lagarde is the Executive Vice President and Chief Operating Offer of Thermo Fisher Scientific Inc. (“Thermo Fisher”), a supplier of analytical instruments, life science solutions, specialty diagnostics, laboratory, pharmaceutical and biotechnology services. He was Executive Vice President of Thermo Fisher from 2019 through 2021. Mr. Lagarde was the Senior Vice President and President, Pharma Services from 2017 to 2019, joining Thermo Fisher as Senior Vice President, Pharma Services through its acquisition of Patheon N.V., a pharma services company, in 2017.

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9. Apr 1, 2020

   As previously announced, Dr. Reshma Kewalramani became the President and Chief Executive Officer of Vertex Pharmaceuticals Incorporated (the "Company") and Dr. Jeffrey M. Leiden transitioned to the role of Executive Chairman of the Company, in each case, effective April 1, 2020. On April 1, 2020, the Company entered into an employment agreement with Dr. Leiden, the terms of which were described in the Current Report on Form 8-K filed by the Company on July 25, 2019 (the "July Form 8-K"). The terms of Dr. Kewalramani's employment arrangements with the Company were also described in the July Form 8-K. Dr. Leiden’s employment agreement, dated April 1, 2020, is filed as Exhibit 10.1 to this Current Report on Form 8-K and the full text of his employment agreement is incorporated by reference herein.

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10. Jul 25, 2019

    On July 25, 2019, Vertex Pharmaceuticals Incorporated (the “Company”) issued a press release announcing Dr. Jeffrey M. Leiden’s upcoming transition to the role of Executive Chairman and the Company’s appointment of Reshma Kewalramani, M.D., as our President and Chief Executive Officer effective April 1, 2020. Effective as of March 31, 2020, Dr. Leiden will cease to be President and Chief Executive Officer of the Company, and, effective April 1, 2020, Dr. Kewalramani, 46, now the Company’s Executive Vice President, Global Medicines Development and Medical Affairs, and Chief Medical Officer, will become the Company’s next President and Chief Executive Officer and will be appointed to serve on the Company’s board of directors (the “Board”). For additional biographical information on Dr.

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11. Jun 5, 2019

    On June 5, 2019, at our 2019 annual meeting of shareholders, our shareholders approved (i) an amendment and restatement of our 2013 Stock and Option Plan that, among other things, increases the number of shares of common stock authorized for issuance under this plan by 5.0 million shares and (ii) an amendment and restatement of our Employee Stock Purchase Plan that, among other things, increases the number of shares of common stock authorized for issuance under this plan by 2.0 million shares. Descriptions of the material terms and conditions of our 2013 Stock and Option Plan and our Employee Stock Purchase Plan are provided in our definitive proxy statement for the 2019 annual meeting of shareholders, which was filed with the Securities and Exchange Commission on April 26, 2019, and are incorporated by reference herein.

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12. Apr 2, 2019

    On March 28, 2019, Charles F. Wagner, Jr. agreed to become our Executive Vice President, Chief Financial Officer, effective April 10, 2019. In connection with Mr. Wagner’s appointment, Paul Silva, who has been serving as our interim Chief Financial Officer since January 2019, will return to his prior role as our Senior Vice President and Corporate Controller. Mr. Wagner, 51, was Chief Financial Officer and Executive Vice President, Finance, of Ortho Clinical Diagnostics, a Carlyle Group portfolio company, from June 2015 to March 2019. In that role, he led the finance, accounting, tax, treasury, global information systems, lender relations, and acquisitions and divestiture groups, as well as shared leadership over several enterprise-wide projects. From July 2012 to June 2015, Mr.

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13. Feb 22, 2019

    (d) Effective February 21, 2019, Lloyd Carney was appointed as a new member of our board of directors. In connection with the appointment of Mr. Carney, the size of our board was increased from nine to ten members. Mr. Carney is expected to join our Audit and Finance Committee. Mr. Carney is the Chairman and Chief Executive Officer of ChaSerg Technology Acquisition Corp., a technology acquisition company. He was the Chief Executive Officer of Brocade Communications Systems Inc., or Brocade, a global supplier of networking hardware and software, from January 2013 until 2017, when it was acquired by Broadcom. Prior to Brocade, he served as Chief Executive Officer of Xsigo Systems, a cloud-based infrastructure solutions provider, until its acquisition by Oracle.

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14. Jan 23, 2019

    (b) On January 23, 2019, Ian Smith was terminated from his positions as our executive vice president and chief operating officer and interim chief financial officer. Mr. Smith’s termination is the result of personal behavior found by us and our board of directors to violate Vertex’s Code of Conduct and values and is unrelated to our financial and business performance. (c) Paul Silva, age 52, our senior vice president and corporate controller, was appointed our interim chief financial officer on January 23, 2019. Additional biographical information regarding Mr. Silva can be found in our Annual Report on Form 10-K for the fiscal year ended December 31, 2017.

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15. Dec 17, 2018

    (b) On December 13, 2018, Thomas Graney notified us he is resigning as our chief financial officer effective immediately. Mr. Graney will continue as an employee and assist in the transition through February 2019. (c) Ian F. Smith, age 52, our executive vice president and chief operating officer and former chief financial officer, assumed the additional role of interim chief financial officer on December 13, 2018. Additional biographical information regarding Mr. Smith can be found in our Annual Report on Form 10-K for the fiscal year ended December 31, 2017.

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Proxy statements (DEF 14A): 2026 · 2025 · 2024 · 2023 · 2022 · 2021

From the company's 10-K XBRL data (SEC companyfacts).

People who stopped filing as an insider of this company. “Last filing” is the last Form 3/4/5, an upper bound on when they left.